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1.
Clinical Anesthesia for the Newborn and the Neonate ; : 889-901, 2023.
Article in English | Scopus | ID: covidwho-20242289

ABSTRACT

COVID-19 pandemic in 2020-2021 affected millions of people including children. Though uncommon, there are few reports of COVID in neonates also. COVID is primarily managed by pediatricians;however, they are involved when providing anesthesia to these neonates for surgery. The role of anesthetists, besides during surgery, has proven to be vital in COVID pandemic for their expertise in airway and ventilatory management, also putting them to the highest risk of exposure. Various testing methods are available, and TrueNAT and RTPCR have emerged as most reliable. Most neonates remain asymptomatic or have mild symptoms;however, RTPCR testing should be done in all at least 72 h of preoperative. Utmost care should be taken during the preoperative evaluation, and in the perioperative period, goal is to prevent transmission of COVID to noninfected HCW involved in the perioperative period, to other newborns and neonates, and also to avoid increasing the severity of the diseases in the positive neonates, while keeping in mind the vulnerability of these babies in combination with their surgical disease and the changing neonatal physiology. COVID care protocols should be followed at all times. Anesthetic considerations remain the same as described in other chapters in the book, in newborns and neonates, both term and preterm. All OT personnel need to don the PPE, which can be problematic especially for the anesthetist, as it restricts the normal unhindered movements, use of stethoscope for chest auscultation for heart rate, respiration, and ETT positioning. Hence, one needs to be very meticulous in IV line and ET placement and their securing to prevent accidental dislodging during positioning and under the drapes. All disposable and non-disposable equipment used for the covid positive baby, should be adequately treated or discarded, as the case may be, after each surgery. Only emergency surgery should be undertaken in COVID-positive neonates to prevent high postoperative morbidity and mortality. There is not much data available in neonates, and most guidelines have been introduced for children and adolescents. Neonatal care has emerged from the experience of the anesthesiologist and from extrapolation of the available pediatric guidelines. Here, we will be discussing COVID in neonates and anesthetic management in COVID-positive neonates undergoing surgery. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023.

2.
Teaching in the Post COVID-19 Era: World Education Dilemmas, Teaching Innovations and Solutions in the Age of Crisis ; : 13-25, 2022.
Article in English | Scopus | ID: covidwho-20232857

ABSTRACT

Universities worldwide are increasingly investing in academic innovation centers that are designed to encourage their students to pursue careers focused on innovation and technology. This chapter explores the educational opportunities of these academic innovation centers during crisis situations by documenting how an academic innovation center at Florida State University - the Innovation Hub - was able to encourage university students to engage in creative problem solving through design thinking, emerging technologies, and experiential learning during the COVID-19 pandemic. The results of these efforts demonstrate that academic innovation centers, during times of global crisis, have a unique opportunity to lead by example, enhancing their educational impact by connecting students directly with real-world challenges as creative problem solvers with the power to improve their communities. © Springer Nature Switzerland AG 2021. All rights reserved.

3.
AIP Conference Proceedings ; 2521, 2023.
Article in English | Scopus | ID: covidwho-20231824

ABSTRACT

Hand hygiene (HH) is a crucial factor for reducing Healthcare Associated Infections (HAIs) in the hospital setting. The current analysis was created to create an intervention methodology to enhance hand hygiene compliance among hospital personnel in a healthcare setting. Covid-19 disease epidemic has additional stressed the need for world-wide development in hand hygiene compliance by the healthcare personnel. Healthcare Associated Infections have been a hot issue for several time periods and Healthcare Associated Infections are the most common adverse results due to the delivery of medical care and treatment. There is unanimity that hand hygiene is the extremely successful way to avoid healthcare associated infections. As healthcare systems fluctuate widely, prevention approaches must be designed appropriately. Hand hygiene, however, remains relevant in all settings, and World Health Organization (WHO) is strongly endorsing alcohol-based hand rubs to interrupt transmission. Nevertheless, very minimal compliance rate amongst the healthcare staff have been reported worldwide. Infected surfaces, especially those that are touched repeatedly by the patient's surroundings, act as reservoirs for pathogens and cause towards pathogen transmission. Therefore, healthcare disinfection requires a thorough approach whereby several strategies may be applied together, risk-based methodologies, to decrease the possibility of HAIs for the patients. In this paper more than 200 articles have been studied from 2016 to 2021 time period and various surveys have been conducted to analyze hand hygiene intervention and studied the various factors involving the patient's situation, medication management behavior of several units, and the type of healthcare employees during and before the Covid-19 pandemic. Based on this study, we evaluated overall hand hygiene compliance rate including the intake of hand wash liquid agent, alcohol-based hand rub (ABHR), the paper wipes, medical waste consumption and personal protective equipment's (gloves, masks etc.) before and after Covid-19 intervention to improve the hand hygiene compliance rate in Abu Dhabi hospitals. © 2023 Author(s).

4.
Cureus ; 15(5): e38485, 2023 May.
Article in English | MEDLINE | ID: covidwho-20238438

ABSTRACT

Background Healthcare workers (HCWs) were compelled to use personal protective equipment (PPE) during the COVID-19 pandemic to prevent cross-transmission. One of the most significant challenges in responding to the COVID-19 pandemic is the consistent and effective use of PPE to avoid staff exposure and infection. This study aimed to detect and evaluate the adverse effects of PPE and determine the associated risk factors. Methodology This cross-sectional study included 186 randomly selected HCWs at Civil Hospital, Ahmedabad, from May 2022 to July 2022. An anonymous self-administered questionnaire was used for data collection, and data analysis was done using descriptive statistics. Results PPE-related adverse effects were noted among 147 HCWs, with a prevalence of 79.03%. Data analysis showed that factors significantly associated with PPE adverse effects in HCWs were age group 20-40 years (chi-squared (χ2) = 4.119, p = 0.04) and female gender (χ2 = 7.153, p = 0.007). Overall, 30.8% of participants had tested positive while on duty during the pandemic. Similarly, adverse effects were associated with PPE use of more than four hours per day and more than three days per week (χ2 = 5.477, p = 0.02 and χ2 = 6.488, p = 0.01, respectively). The majority of HCWs expressed indentation and pain on the back of the ear (52.7%) and pressure-related injury (39.8%) as adverse effects after wearing masks; skin soaking in sweat (54.83%) due to gloves; profuse sweating due to gown (64.28%); fogging (65.26%) due to googles and face-shield; and discomfort (61.29%). Conclusions The prevalence of adverse effects related to wearing PPE was alarmingly high among HCWs. The major risk factors were age, female sex, and duration of use. Although the majority of healthcare personnel have received vaccinations, the use of PPE has not altered, and severe skin reactions continue to be a global issue with no known solution. To further understand the problem, national data for the impacted healthcare professionals could be helpful. Furthermore, workplace prevention programs are necessary.

5.
Front Public Health ; 11: 1155980, 2023.
Article in English | MEDLINE | ID: covidwho-20234940

ABSTRACT

The need to improve career development and training for residential aged care workers in Australia to achieve required essential competencies, including infection prevention and control competencies, has been repeatedly highlighted. In Australia long-term care settings for older adults are known as residential aged care facilities (RACFs). The COVID-19 pandemic has brought to light the lack of preparedness of the aged care sector to respond to emergencies, and the urgent need to improve the infection prevention and control training in residential aged care facilities. The government in the Australian State of Victoria allocated funds to support older Australians in RACFs, including funds toward infection prevention and control training of RACF staff. The School of Nursing and Midwifery at Monash University addressed some of these challenges in delivering an education program on effective infection prevention and control practices to the RACF workforce in Victoria, Australia. This was the largest state-funded program delivered to RACF workers to date in the State of Victoria. The aim of this paper is to provide a community case study, where we share our experience of program planning and implementation during early stages of the COVID-19 pandemic and lessons learned.


Subject(s)
COVID-19 , Humans , Aged , Victoria/epidemiology , COVID-19/epidemiology , COVID-19/prevention & control , Pandemics/prevention & control , Infection Control , Workforce
6.
UCL Open Environ ; 3: e022, 2021.
Article in English | MEDLINE | ID: covidwho-20232146

ABSTRACT

During the coronavirus (COVID-19) pandemic, the UK government mandated the use of face masks in various public settings and recommended the use of reusable masks to combat shortages of medically graded single-use masks in healthcare. To assist decision-making on the choice of masks for future pandemics, where shortages may not be a contributing factor, the University College London (UCL) Plastic Waste Innovation Hub has carried out a multidisciplinary comparison between single-use and reusable masks based on their anatomy, standalone effectiveness, behavioural considerations, environmental impact and costs. Although current single-use masks have a higher standalone effectiveness against bacteria and viruses, studies show that reusable masks have adequate performance in slowing infection rates of respiratory viruses. Material flow analysis (MFA), life cycle assessment (LCA) and cost comparison show that reusable masks have a lower environmental and economic impact than single-use masks. If every person in the UK uses one single-use mask each day for a year, it will create a total of 124,000 tonnes of waste, 66,000 tonnes of which would be unrecyclable contaminated plastic waste (the masks), with the rest being the recyclable packaging typically used for transportation and distribution of masks. Using reusable masks creates >85% less waste, generates 3.5 times lower impact on climate change and incurs 3.7 times lower costs. Further behavioural research is necessary to understand the extent and current practices of mask use; and how these practices affect mask effectiveness in reducing infection rates. Wearing single-use masks may be preferred over reusable masks due to perceptions of increased hygiene and convenience. Understanding behaviour towards the regular machine-washing of reusable masks for their effective reuse is key to maximise their public health benefits and minimise environmental and economic costs.

7.
Am J Infect Control ; 2023 May 30.
Article in English | MEDLINE | ID: covidwho-2327902

ABSTRACT

BACKGROUND: The study objective was to quantify infection rate trends for central line-associated bloodstream infections (CLABSIs) and catheter-associated urinary tract infections (CAUTIs) in 89 Alabama hospitals from 2015 to 2021 to analyze how the COVID-19 pandemic impacted health care delivery. METHODS: Retrospective analysis of CLABSI and CAUTI rates, from 89 Alabama hospitals via data from the Alabama Department of Public Health from 2015 to 2021. RESULTS: Based on our modeling strategies, there was a statistically significant decrease in rates of CAUTIs from 2015 to 2019 at an estimated rate of 7% per year (P = 0.0167) and CLABSIs from 2015 to 2018 at an estimated rate of 13% per year (P < .001) in these hospitals. In 2020, the CAUTI and CLABSI rates began increasing at a modeled rate of 29% per year (P = .001) and 35% per year (P < .001) respectively. DISCUSSION: A review of potential causes for the elevated rate of health care-associated infections illustrated that certain practices may have contributed to increased CAUTI and CLABSI rates. Utilizing staff from noncritical care areas with less experience in health care-associated infection prevention, batching of tasks to conserve personal protective equipment, and a nationwide mental health crisis could have affected infection prevention bundle compliance. CONCLUSIONS: An increase in CAUTIs and CLABSIs was observed during the pandemic, likely due to the large volume of patients requiring advanced medical care and subsequent depleted resources.

8.
COVID-19 and a World of Ad Hoc Geographies: Volume 1 ; 1:1325-1340, 2022.
Article in English | Scopus | ID: covidwho-2324397

ABSTRACT

COVID-19 illuminates the contradictions of U.S. relations with Asia economically, culturally, and socially in relation to Asian immigrant labor, goods and manufacturing, and with Asian Americans. We explore the importance of Asia as a supplier of labor and goods to the U.S. health system in order to analyze how the U.S. navigates its interdependence with Asia while demonizing Asians/Americans and attempting to protect its borders metaphorically and materially. We analyze how Asian American nurses are fighting the battle against the pandemic on the frontlines while also fighting the stereotypes and stigma that some Americans may have against them because they associate Asian Americans with the spread of COVID-19. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

9.
Smart and Functional Textiles ; : 721-750, 2023.
Article in English | Scopus | ID: covidwho-2323548

ABSTRACT

The COVID-19 pandemic has provided a great challenge with unprecedented demand for personal protective equipment (PPE) during the initial stages of the outbreak. However, it has also been a tremendous opportunity for the textile industry to innovate within the sphere of PPE as textile products formed the first line of defence against this novel coronavirus giving time to the scientists to develop a vaccine. This chapter provides an overview of the challenges presented by COVID-19 and the key constituent parts of PPE for medical personnel during this time. The construction and features of these items, in addition to the regulations governing these important items of PPE, are discussed. Additionally, the future direction of PPE, particularly with regard to single-use items and the sustainability of PPE supplies, is considered. © © 2023 Walter de Gruyter GmbH, Berlin/Boston. All rights reserved.

10.
COVID-19 and a World of Ad Hoc Geographies: Volume 1 ; 1:1679-1699, 2022.
Article in English | Scopus | ID: covidwho-2323263

ABSTRACT

The purpose of this chapter is to explore the challenges faced in nursing homes during the COVID-19 pandemic. The chapter begins with a review of characteristics of nursing home facilities relevant to the coronavirus pandemic. Next, a personal interview with a nurse/administrator in rural Kentucky covers a broad range of topics, including issues with personal protective equipment (PPE), changes to routine care and activities of residents, effects of lockdown on patients and staff, and lessons learned. The discussion considers differences in effects on rural versus urban nursing homes. Conclusions sum up the material discussed and relay information about the coronavirus situation currently (August 2021). © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

11.
COVID-19 Critical and Intensive Care Medicine Essentials ; : 53-60, 2022.
Article in English | Scopus | ID: covidwho-2321845

ABSTRACT

Intubation and invasive mechanical ventilation are often unavoidable in most severe cases of COVID-19 pneumonia;however, deciding the optimum timing and best practices of intubation is challenging. The decision to proceed with intubation should be based on an integrated patient evaluation and not limited to the assessment of the severity of hypoxemia alone. Intubation is a maneuver exposing the operator to a high risk of contamination, therefore adequate personal protection equipment is mandatory. Benefits of intubation over noninvasive respiratory support include reduction or suppression of the respiratory drive, reduction of the basal metabolism and allowance of maintaining protective mechanical ventilation. On the other hand, risks are related to the need for sedation, the presence of an artificial airway and exposure to mechanical ventilation, which may result in overlapping ventilator-associated bacterial pneumonia and ventilator-induced lung injury. Balancing between risks and benefits of intubation in this context is challenging and the optimum timing of intubation remains largely an open question. This chapter discusses the clinical, technical, and safety aspects that deserve to be considered when considering intubation in patients with severe COVID-19-related acute respiratory failure. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

12.
Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications ; : 471-481, 2021.
Article in English | Scopus | ID: covidwho-2326735

ABSTRACT

Treatment of COVID-19 patients is an immense administrative as well as clinical challenge. The setting up of a dedicated COVID-19 care centre within a short time span, adequate manpower deployment, healthcare worker education and training, provision of facilities for donning and doffing and waste disposal were some of the unique administrative problems. On the other hand, as clinicians we faced enormous hurdles in attempting to treat a disease on which there was no established knowledge and no defined, well-proven treatment protocols and which could strike anyone, anywhere in myriad ways. Coupled with this difficulty in diagnosis and treatment was the challenge of serving COVID-19 patients of every age and clinical requirement, under one roof. Healthcare workers faced a tough time, handling physical discomfort while working for long hours in PPE, along with the fear and apprehension of contracting the infection in the line of duty, and carrying it back home. Mental health issues abounded, both amongst the patients and their caregivers, due to heightened fear, anxiety and loneliness. We share our experience in dealing with the pandemic, the administrative and clinical challenges we faced and some of the ways we overcame them. We further share some of the insights we gleaned from this experience, which may help in better preparation for the future. © The Author(s), under exclusive licence to Springer Nature Singapore Pte Ltd. 2021.

13.
Health Crisis Management in Acute Care Hospitals: Lessons Learned from COVID-19 and Beyond ; : 99-121, 2022.
Article in English | Scopus | ID: covidwho-2325118

ABSTRACT

The coronavirus pandemic stretched healthcare resources and infrastructure worldwide. The Emergency Department (ED) is a crucial component in the frontline response to the pandemic. In this chapter, we discuss the logistical and operational challenges faced, the innovative solutions employed, and the lessons learned in our ED as we strived to overcome this unprecedented challenge. Whilst we will share much of what we learned, what we did, and what we believe was responsible for our many successes, at the same time, we are left with a sadness that our healthcare systems (and ‘our' could be applied locally to our community, nationally to our country, and globally to our planet) were simply not designed nor prepared to properly confront a pandemic. The number of patient deaths we witnessed still feels somewhat incomprehensible and scarring. We do, however, hope that our learnings may help inform decisions at other EDs, help prepare us for future crises, and, if nothing else, confers confidence in the ED's ability to overcome this pandemic. © SBH Health System 2022.

14.
Mar Pollut Bull ; 192: 115031, 2023 Jul.
Article in English | MEDLINE | ID: covidwho-2324012

ABSTRACT

Personal Protective Equipment (PPE) is a new world of waste during the COVID-19 pandemic. In this baseline study, the occurrence of PPE faces masks were assessed on the eleven beaches of Kanyakumari, India concerning the abundance, spatial distribution, and chemical characterization (ATR-FTIR spectroscopy). A total of 1593 items/m2 of PPE face masks and their mean density of 0.16 PPE/m2, ranging from 0.02 to 0.54 PPE/m2 were determined in the study area. Kanyakumari beach (n = 430 items/m2) has the highest concentration of masks (26.99 %), with a mean density of 0.54 m2 due to recreational, sewage disposal, and tourism activities. This is perhaps the most important study describing the scientific data that focuses on the significant effects of communal activities and accessibility on COVID-19 PPE face mask pollution. It also highlights the need for sufficient management facilities to optimize PPE disposal.


Subject(s)
COVID-19 , Humans , COVID-19/prevention & control , Masks , Pandemics , Personal Protective Equipment , India , Plastics
15.
J Int Soc Respir Prot ; 39(1): 1-25, 2022.
Article in English | MEDLINE | ID: covidwho-2321971

ABSTRACT

Background: Coronavirus disease 2019 (COVID-19) has led to severe shortages of filtering facepiece respirators (FFRs). As a result, extended use, limited reuse, and FFR decontamination have been utilized to extend the life of single-use FFRs. Although some studies have raised concerns that reuse could affect the FFR's ability to form a seal, no comprehensive literature review of the effect of extended use or limited reuse on FFR seal exists. Objective: The goal of this review was to assess the effect of extended use and reuse on respirator fit, with and without decontamination. Methods: Searches of PubMed and Medrxiv yielded 24 papers that included assessment of fit after extended use or limited reuse on a human. One additional handpicked paper was added. Results: Studies report a wide variation in the number of donnings and doffings before fit failure between different models of respirators. Additionally, while seal checks lack sufficient sensitivity to reliably detect fit failures, individuals who failed fit testing were often able to pass subsequent tests by re-positioning the respirator. Even with failure, respirators often maintained a substantially higher level of fit than a surgical mask, so they may still provide a level of protection in crisis settings. Conclusion: Based on currently available data, this literature review was unable to establish a consensus regarding the amount of time a respirator can be worn or the number of uses before fit failure will occur. Furthermore, variations in reuses before fit failure between different models of N95 respirators limit the ability to offer a comprehensive recommendation of greater than one reuse or a specific amount of wear time.

16.
Prep Biochem Biotechnol ; : 1-20, 2023 May 07.
Article in English | MEDLINE | ID: covidwho-2318432

ABSTRACT

Fifty percent of the overall operational expenses of biorefineries are incurred during enzymatic-saccharification processes. Cellulases have a global-market value of $1621 USD. Dearth of conventional lignocelluloses have led to the exploration of their waste stream-based, unconventional sources. Native fungus-employing cellulase-production batches fail to yield sustained enzyme titers. It could be attributed to variations in the enzyme-production broth's quasi-dilatant behavior, its fluid and flow properties; heat and oxygen transfer regimes; kinetics of fungal growth; and nutrient utilization. The current investigation presents one of the first-time usages of a substrate mixture, majorly comprising disposed COVID-19 personal protective-equipment (PPE). To devise a sustainable and scalable cellulase-production process, various variable-regulated, continuous-culture auxostats were performed. The glucose concentration-maintaining auxostat recorded consistent endoglucanase titers throughout its feeding-cum-harvest cycles; furthermore, it enhanced oxygen transfer, heat transfer co-efficient, and mass transfer co-efficient by 91.5, 36, and 77%, respectively. Substrate-characterization revealed that an unintended, autoclave-based organsolv pretreatment caused unanticipated increases in endoglucanase titers. The cumulative lab-scale cellulase-production cost was found to be $16.3. The proposed approach is economical, and it offers a pollution-free waste management process, thereby generating carbon credits.

17.
Emerg Med Australas ; 35(3): 483-488, 2023 06.
Article in English | MEDLINE | ID: covidwho-2315503

ABSTRACT

OBJECTIVES: To examine workload, thermal discomfort and heat-related symptoms among healthcare workers (HCWs) in an Australian ED during the COVID-19 pandemic. METHODS: A cross-sectional study design was employed among HCWs in an ED at a metropolitan hospital in Brisbane, Australia. Respondents provided demographic information including their self-reported age, sex, height, weight, role (e.g. doctor, nurse), and whether they wore personal protective equipment (PPE) during their shift, rated as either Full PPE, Partial PPE, or usual uniform or scrubs. The workload of HCWs was assessed with the National Aeronautics and Space Administration's task load index (NASA-TLX). Thermal discomfort was evaluated using scales from the International Organisation for Standardisation. Responders rated their subjective heat illness using the Environmental Symptoms Questionnaire. RESULTS: Fifty-nine HCWs completed the survey (27 male, 31 female, one prefer not to answer). Overall workload from the NASA-TLX was 64.6 (interquartile range [IQR] 56.5-73.3) for doctors, 72.5 (IQR 63.3-83.3) for nurses and 66.7 (IQR 58.3-74.17) for other staff, representing moderate to high ratings. Eighty-one percent reported thermal sensation to be slightly warm, warm, or hot, and 88% reported being uncomfortable, ranging from slightly to extremely. Ninety-seven percent reported at least one heat-strain symptom. More than 50% reported light-headedness or headache and approximately 30% reported feeling dizzy, faint, or weak. CONCLUSIONS: ED HCWs experience thermal discomfort when wearing PPE. Combined with their workloads, HCWs experienced symptoms related to heat strain. Therefore, careful consideration should be given to managing heat strain among HCWs when wearing PPE in an ED.


Subject(s)
COVID-19 , Male , Humans , Female , COVID-19/epidemiology , COVID-19/prevention & control , Workload , Hot Temperature , Pandemics/prevention & control , Cross-Sectional Studies , Australia/epidemiology , Personal Protective Equipment , Health Personnel , Surveys and Questionnaires , Emergency Service, Hospital
18.
Sci Total Environ ; 887: 164164, 2023 Aug 20.
Article in English | MEDLINE | ID: covidwho-2315235

ABSTRACT

During the COVID-19 pandemic, people used personal protective equipment (PPE) to lessen the spread of the virus. The release of microplastics (MPs) from discarded PPE is a new threat to the long-term health of the environment and poses challenges that are not yet clear. PPE-derived MPs have been found in multi-environmental compartments, e.g., water, sediments, air, and soil across the Bay of Bengal (BoB). As COVID-19 spreads, healthcare facilities use more plastic PPE, polluting aquatic ecosystems. Excessive PPE use releases MPs into the ecosystem, which aquatic organisms ingest, distressing the food chain and possibly causing ongoing health problems in humans. Thus, post-COVID-19 sustainability depends on proper intervention strategies for PPE waste, which have received scholarly interest. Although many studies have investigated PPE-induced MPs pollution in the BoB countries (e.g., India, Bangladesh, Sri Lanka, and Myanmar), the ecotoxicity impacts, intervention strategies, and future challenges of PPE-derived waste have largely gone unnoticed. Our study presents a critical literature review covering the ecotoxicity impacts, intervention strategies, and future challenges across the BoB countries (e.g., India (162,034.45 tons), Bangladesh (67,996 tons), Sri Lanka (35,707.95 tons), and Myanmar (22,593.5 tons). The ecotoxicity impacts of PPE-derived MPs on human health and other environmental compartments are critically addressed. The review's findings infer a gap in the 5R (Reduce, Reuse, Recycle, Redesign, and Restructure) Strategy's implementation in the BoB coastal regions, hindering the achievement of UN SDG-12. Despite widespread research advancements in the BoB, many questions about PPE-derived MPs pollution from the perspective of the COVID-19 era still need to be answered. In response to the post-COVID-19 environmental remediation concerns, this study highlights the present research gaps and suggests new research directions considering the current MPs' research advancements on COVID-related PPE waste. Finally, the review suggests a framework for proper intervention strategies for reducing and monitoring PPE-derived MPs pollution in the BoB countries.


Subject(s)
COVID-19 , Humans , Ecotoxicology , Ecosystem , Plastics/toxicity , Pandemics , Microplastics , Personal Protective Equipment
19.
Pathogens ; 11(1)2022 Jan 10.
Article in English | MEDLINE | ID: covidwho-2315199

ABSTRACT

The arrival of SARS-CoV-2 to Aotearoa/New Zealand in February 2020 triggered a massive response at multiple levels. Procurement and sustainability of medical supplies to hospitals and clinics during the then upcoming COVID-19 pandemic was one of the top priorities. Continuing access to new personal protective equipment (PPE) was not guaranteed; thus, disinfecting and reusing PPE was considered as a potential alternative. Here, we describe part of a local program intended to test and implement a system to disinfect PPE for potential reuse in New Zealand. We used filtering facepiece respirator (FFR) coupons inoculated with SARS-CoV-2 or clinically relevant multidrug-resistant pathogens (Acinetobacter baumannii Ab5075, methicillin-resistant Staphylococcus aureus USA300 LAC and cystic-fibrosis isolate Pseudomonas aeruginosa LESB58), to evaluate the potential use of ultraviolet-C germicidal irradiation (UV-C) or dry heat treatment to disinfect PPE. An applied UV-C dose of 1000 mJ/cm2 was sufficient to completely inactivate high doses of SARS-CoV-2; however, irregularities in the FFR coupons hindered the efficacy of UV-C to fully inactivate the virus, even at higher UV-C doses (2000 mJ/cm2). Conversely, incubating contaminated FFR coupons at 65 °C for 30 min or 70 °C for 15 min, was sufficient to block SARS-CoV-2 replication, even in the presence of mucin or a soil load (mimicking salivary or respiratory secretions, respectively). Dry heat (90 min at 75 °C to 80 °C) effectively killed 106 planktonic bacteria; however, even extending the incubation time up to two hours at 80 °C did not completely kill bacteria when grown in colony biofilms. Importantly, we also showed that FFR material can harbor replication-competent SARS-CoV-2 for up to 35 days at room temperature in the presence of a soil load. We are currently using these findings to optimize and establish a robust process for decontaminating, reusing, and reducing wastage of PPE in New Zealand.

20.
Regional Studies in Marine Science ; 62:102966, 2023.
Article in English | ScienceDirect | ID: covidwho-2308232

ABSTRACT

It is widely recognized that the measures adopted during the pandemic resulted in a significant number of face masks entering marine environments. One key aspect is to investigate the behavior of such contaminants in coastal environments. In the present study, in situ experiments were carried out to investigate the physicochemical changes of two types of face masks, as well as their interaction with intertidal biota. Chemical analyses showed no notorious signs of photo-oxidation while confirming that face masks are entirely composed of synthetic polymers. However, scanning electron microscopy showed an affectation of the physical structure on the outer layer of KN95 respirators, as well as the presence of environmental elements accumulating. Interaction with intertidal biota suggested that face masks serve as a suitable substrate and hiding spot for bivalves and polychaetes. Investigating the alteration of such contaminants in the intertidal shore provides new insights into their behavior after entering the ocean.

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